Table 1.

TKTD parameters and study-specific scaled functional response in Experiments 1 and 2

Symbol	Unit	DEB definition	Value
${\dot{h}}_0$	d−1	Background hazard rate	0.001545
${\dot{k}}_e$	d−1	Elimination rate constant	0.0001283
$c_0$	ng/L	Threshold concentration for effects on feeding	2.282e−09
$c_T$	ng/L	Tolerance concentration	2.159
$c_{0\text{s}}$	ng/L	Threshold concentration for effects on survival	0.6908
b	d−1	Killing rate	0.01965
$f_{\text{cW0}}$	−	Scaled functional response for Experiment 1	0.48
$f_{\text{A}}$	−	Scaled functional response for cohort A Experiment 2	0.73
$f_{\text{B}}$	−	Scaled functional response for cohort B Experiment 2	0.53
$f_{\text{C}}$	−	Scaled functional response for cohort C Experiment 2	0.73