Table 2.

Application of the Critical Appraisal Skills Programme tool [12]

Quantitative ultrasound device	Study	Year	Type of study	Are the results of the study valid?	What are the results?	Will the results help locally?
Omnisense 7000P	Mercy et al. [2]	2007	Cohort	+	+	±
	Ashmeade et al. [7]	2007	Case control	±	±	±
	McDevitt et al. [8]	2007	Cohort	+	+	±
	Zuccotti et al. [13]	2011	Cohort	±	+	±
	Tansug et al. [14]	2011	Case control	±	+	±
	Litmanovitz et al. [18]	2007	Randomised controlled trial	±	+	±
	Liao et al. [19]	2005	Case control	±	+	–
	McDevitt et al. [20]	2005	Cohort	±	+	±
	Altuncu et al. [21]	2007	Diagnostic accuracy	±	±	±
	Chen et al. [22]	2012	Case control	±	+	±
	Littner et al. [24]	2004	Case control	±	±	±
	Fewtrell et al. [25]	2008	Cohort	±	±	±
	Chen et al. [26]	2010	Randomised controlled trial	±	+	±
	Litmanovitz et al. [29]	2003	Randomised controlled trial	+	+	±
	Pereda et al. [30]	2003	Cohort	±	+	±
	Littner et al. [31]	2003	Cohort	±	±	±
	Littner et al. [33]	2004	Case control	±	±	±
	Littner et al. [34]	2005	Case control	±	±	±
	Teitelbaum et al. [35]	2006	Case control	±	±	±
	Chen et al. [38]	2007	Case control	±	+	±
	Ahmad et al. [37]	2010	Case control	±	±	±
	Liao et al. [38]	2010	Case control	–	±	±
	Erdem et al. [40]	2015	Randomised controlled trial	±	+	±
DBM Sonic	Gonnelli et al. [15]	2004	Cohort	±	+	±
	Betto et al. [16]	2014	Cohort	±	+	±
	Ritschl et al. [17]	2005	Cohort	±	+	±
	Rubinacci et al. [32]	2003	Case control	±	+	±
	Savino et al. [39]	2013	Cohort	±	+	±
Osteon KIV	Rack et al. [23]	2012	Case control	–	+	±

+ Yes

- No

± Unable to tell