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. 2018 Jun 16;48(11):1537–1549. doi: 10.1007/s00247-018-4161-5

Table 4.

Postnatal trend in quantitative ultrasonography values

Reference Year Quantitative ultrasound device Site/parameter Trend of speed of sound/bone transmission time values postnatally (preterm) Trend of speed of sound/ bone transmission time values postnatally (term) Comments
Mercy et al. [2] 2007 Omnisense 7000P Tibia/SOS Decreasing The overall trend in tibial SOS showed a decrease with postnatal age.
Ashmeade et al. [7] 2007 Omnisense 7000P Tibia/SOS Decreasing There was a significant decrease over time for entire cohort of preterm infants.
Tansug et al. [14] 2011 Omnisense 7000P Tibia/ SOS Decreasing SOS values of preterm infants decreases until 2nd month of life.
Gonnelli et al. [15] 2004 DBM Sonic Humerus/BTT, SOS Decreasing in SOS
Increasing in BTT
Decrease in SOS values for term infants at 12-months follow-up. Steady increases in BTT for term infants after birth at 12-months follow up.
Betto et al. [16] 2014 DBM Sonic Metacarpal/BTT, SOS Decreasing Decreasing Deflection of metacarpal BTT from birth to 3rd week of life, followed by increase in this parameter during first few months of life.
Ritschl et al. [17] 2005 DBM Sonic Second metacarpal/ BTT, SOS Decreasing in SOS
Increasing in metacarpal BTT
Decreasing in SOS Decline in SOS values for up to 6 months in term and preterm infants, then increasing trend up to 18 months of life.
Steady increase in metacarpal BTT after birth in preterm infants.
Litmanovitz et al. [18] 2007 Omnisense 7000P Tibia/ SOS Decreasing Bone SOS decreases during the first 4 postnatal weeks in very low birth weight premature infants.
Liao et al. [19] 2005 Omnisense 7000P Tibia/SOS Decreasing The SOS of infants showed an inverse correlation with postnatal age, and the decrease of bone SOS with age in premature infants was more marked than in full-term infants.
Altuncu et al. [21] 2007 Omnisense 7000P Tibia/SOS Decreasing Serial assessment of tibia SOS z-scores of preterm infants showed that tibia SOS z-scores of preterm infants at term-CA (corrected age) were significantly lower than the scores at first postnatal week of life.
Rack et al. [23] 2012 Osteoson KIV 4 different sites/SOS Decreasing Rapid decline in SOS values in first few weeks of life, plateauing after 40 weeks post-conceptual age.
Fewtrell et al. [25] 2008 Omnisense 7000P Tibia/SOS Decreasing Both absolute and z-scores relative to cross-sectional reference data fell during the postnatal period.
Litmanovitz et al. [29] 2003 Omnisense 7000P Tibia/SOS Decreasing
Rubinacci et al. [32] 2003 DBM Sonic Humerus/BTT, SOS Decreasing
Savino et al. [39] 2013 DBM sonic Metacarpal/BTT, SOS Decreasing Decreasing trend of SOS values lasted up to 240 days, followed by slow increases in next months.

BTT bone transmission time, SOS speed of sound