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. 2018 Sep 18;5:123. doi: 10.3389/fcvm.2018.00123

Table 1.

Case reports of successful ablation of PVCs triggering VF.

References Patient history Mapping and ablation Outcome
Ashida et al. (50) 18 y.o female Syncope Septal RVOT No VF recurrence after 3 years
Kusano et al. (51) 65 y.o female Syncope RVOT No VF recurrence after 18 months
Takatsuki et al. (52) 62 y.o male Postero-septal RVOT No VF recurrence after 20 months
Saliba et al. (53) 41 y.o female PVC coupling interval = 240 ms Duration 140 ms Inferolateral border of the right ventricle Late sharp potential recorded in sinus rhythm and preceding the PVCs No VF recurrence after 6 months
Betts et al. (54) 27 y.o male Coupling interval 260–300 ms Free wall of the RVOT Sharp potential 80 ms before PVC onset No VF recurrence after 11 months of follow-up
Pasquie et al. (55) 3 patients, mean age 62 y.o VF during fever episodes Coupling intervals = 240 and 320 ms Purkinje potential preceding the PVC (anterior RV) No VF recurrence after 9, 18 and 22 months
Kohsaka et al. (56) 21 y.o female Electrical storm Purkinje from the right bundle preceding the PVC initiation VF by 72 ms No VF recurrence after 12 months
Naik et al. (57) 24 y.o male Syncope Coupling interval = 280–320 ms 2 PVC morphologies = RVOT + RV apex Few PVCs recorded during the procedure Ablation based on pacemapping and targeting Purkinje potential in the RV apex VF recurrence after 9 months due to PVCs of similar morphology Redo ablation was associated with VF Freedom after 1 year-follow-up
Cho et al. (58) 17 y.o male Aborted sudden cardiac death due to IVF Coupling interval = 360 ms Ablation at the anterolateral wall of the RVOT based on the earliest activation site and pacemapping Acute success with no VF/PVT recurrence during the 2 weeks after the procedure
Szumowski et al. (59) 25 y.o female syncope 150 ICD therapies in 9 years PVCs originating from the Purkinje network No VF recurrence after 2 years
Saba et al.(60) 10 y.o male syncope Atrial fibrillation 30 ICD shocks in 2 months 4 PVC morphologies: 2 short coupled (268+/110 ms) with a large QRS (161 ± 7 ms) 2 longer coupled PVCs (422 ± 25 ms) and narrower QRS (118 ± 9 ms) Mapping performed using a basket catheter No VF recurrence after 21 months using quinidine
Santoro et al.(13) 5 patients, mean age 39 ± 12 years Multiple ICD shocks and electrical storm PVCs arising from the left ventricular posteromedial papillary muscle in 4 cases and from the right ventricular postero lateral papillary muscle in 1 case. No VF recurrence after 58 ± 11 months
Nagase et al.(61) 29 y.o female Multiple ICD shocks for VF episodes PVC with different morphologies Ablation targeting earliest anterior and posterior Purkinje potentials Recurrence of 3 VF episodes after 96 months No VF recurrence after administration of atenolol and disopyramide
Kleissner et al.(62) Male Electrical storm 2 PVCs initiating VF The first arising from the right Purkinje preceding the PVC by 28 ms. The second arising from the RVOT.
Rosu et al., (63) 39 y.o male Multiple syncopes PVCs arising from the right Purkinje preceding the PVC by 15 ms. 2 early recurrences of VF episodes initiated by PVC s from the RV with different morphologies. No VF recurrence after 3 years
Chan and Sy (64) 2 patients = 40 and 24 y.o females syncope and cardiac arrest respectively PVCs arising from the posterior fascicle in the first case and from the RVOT in the second case No VF recurrence after 17 and 42 months respectively
Ho et al. (65) 44 y.o male Electrical storm PVCs arising from the moderator band mapped using the Pentaray catheter Purkinje potentials preceding the PVC by 103 ms Ablation targeted Purkinje potentials at the moderator band No VF recurrence after ablation
Martin et al. (66) 32 y.o male Syncope PVC arising from the posterior fascicle Purkinje potentials preceding the PVC by 34 ms Ablation based on pacemapping and the site of earliest activation Recurrence of 1 VF episode after 2 year follow-up

ICD, implantable cardioverter defibrillator; PVC, premature ventricular contraction; PVT, polymorphic ventricular tachycardia; RV, right ventricle; RVOT, right ventricular outflow tract; VF, ventricular fibrillation.