Table 3.
Ligands currently used for adenosine receptors classification.
| Ligand Type | Abbrev. | Ligand | Adenosine Receptor Subtype |
|---|---|---|---|
| AGONIST | ADO | Adenosine | A1, A2A, A2B, A3 |
| NECA | 5′-N-Ethylcarboxamidoadenosine | A1, A2A, A2B, A3 | |
| CPA | N6-Cyclopentyladenosine | A1 | |
| CCPA | 2-Chloro-CPA | A1 | |
| CGS 21680 | 2-p-(2-Carboxyethyl)phenethylamino-5′-N-ethylcarboxamidoadenosine hydrochloride | A2A | |
| IB-MECA | 1-Deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-N-methyl-b-d-ribofuranuronamide | A3 | |
| 2Cl-IB-MECA | 2-Chloro-N6-(3-iodobenzyl)-5′-(N-methylcarbamoyl)adenosine | A3 | |
| ANTAGONIST | Teophylline | 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione | A1, A2A, A2B, A3 |
| Caffeine | 1,3,7-Trimethylpurine-2,6-dione | A1, A2A | |
| DPCPX | 1,3-Dipropyl-8-cyclopentylxanthine | A1 | |
| SCH 58261 | 5-Amino-7-(2-phenylethyl)-2-(2-furyl)-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine | A2A | |
| ZM 241385 | 4-(2-[7-Amino-2-[2-furyl]-[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-yl-amino]ethyl)phenol | A2A | |
| MRS 1754 | N-(4-Cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,4,5,6,7-hexahydro-1H-purin-8-yl)-phenoxy]acetamide | A2B | |
| MRS 1706 | N-(4-Acetylphenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]acetamide | A2B | |
| MRS 1220 | N-[9-Chloro-2-(2-furanyl)[1,2,4]-triazolo[1,5-c]quinazolin-5-yl]benzene acetamide | A3 | |
| MRS 1523 | 2,3-Diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate | A3 |