Figure 8.

Cordycepin inhibited expression of EMT markers in xenograft tumors. Immunohistochemical staining was performed using antibodies against E-cadherin and vimentin. It showed that E-cadherin expression increased after cordycepin treatment (a: control group, b: 50 mg/kg cordycepin group). Vimentin staining intensity decreased after cordycepin treatment (c: control group, d: 50 mg/kg cordycepin group). The asterisk (**) represented areas of non-tumor part, which acted as an internal negative control for the IHC staining.