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. 2017 Mar 23;22(4):506. doi: 10.3390/molecules22040506

Table 2.

The average percent cell viability and percent tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and IL-6 inhibition of the RAW264.7 cells treated with various concentrations of compounds 1 and 2 as well as dexamethasone with 1 μg/mL of LPS. Data are expressed as mean ± SD (standard deviation) of triplicates for each experiment.

Compounds Concentration (μM) Mean % Viability Mean % TNF-α Inhibition Mean % IL-1β Inhibition Mean % IL-6 Inhibition
10 96.9 ± 2.6 22.6 ± 1.6 28.6 ± 1.9 23.8 ± 2.1
1 20 94.8 ± 4.3 28.9 ± 2.7 45.3 ± 3.1 54.4 ± 2.9
30 95.0 ± 3.7 51.3 ± 4.9 55.9 ± 3.9 78.6 ± 5.0
10 97.4 ± 2.8 18.7 ± 1.3 12.5 ± 0.8 18.1 ± 1.2
2 20 95.2 ± 5.6 28.2 ± 3.1 23.6 ± 2.5 37.0 ± 3.2
30 96.0 ± 3.8 51.1 ± 4.7 43.3 ± 2.6 85.4 ± 5.3
10 95.8 ± 2.9 58.3 ± 4.2 62.1 ± 4.3 58.7 ± 2.3
Dexamethasone 20 101.2 ± 3.6 72.4 ± 3.2 69.7 ± 5.8 82.9 ± 4.7
30 97.2 ± 5.8 86.4 ± 6.2 80.4 ± 7.3 91.5 ± 7.9