Figure 1.

MicroRNA-7-5p (mir-7-5p) is upregulated in cisplatin-resistant cervical cancer cells and is associated with increased cell survival. (A) The expression of microRNA-7-5p (mir-7-5p) in cervical cancer tissues and adjacent non-cancerous tissues was detected by quantitative real-time reverse transcription-polymerase chain reaction (qRT-PCR). (B) The IC₅₀ of cisplatin of cervical cell treated with increasing concentration of cisplatin. (C, D) The expression of miR-7-5p in cisplatin-resistant cervical cancer cells was detected by qRT-PCR. (E) The apoptosis rate of the cisplatin-resistant cells with indicated treatment were measured by a flow cytometry assay. * p<0.05, ** p<0.01, ns – no significance.