Table 1.
The cytotoxic activity (IC50) values of 1 and 2 against human cancer cells. *
Compound | IC50 (mM) | ||||
---|---|---|---|---|---|
A 549 | HepG2 | HCT116 | MCF-7 | PC-3 | |
1 | 15.6 | 15.1 | >20 | 15.5 | 17.9 |
2 | 15.9 | 15.3 | 17.9 | 17.9 | >20 |
* A549 (lung carcinoma cells); HepG2 (hepatocellular carcinoma cells; HCT116 (colorectal carcinoma cells); MCF-7 (Breast cancer cells) and PC-3 (prostate cancer cells). All cells were incubated with compounds 1 or 2 for 72 h.