Table 2.

Association Between Hypothyroidism with Hospitalization Risk, Stratified by Underlying Cardiovascular Disease Status

			Unadjusted		Adjusted		Adjusted (including amiodarone)
	# of events	Risk time	HR [CI]	p	HR [CI]	p	HR [CI]	p
CHF
Yes	124	3.75	1.22 [1.02–1.43]	0.001	1.86 [1.17–2.94]	0.006	1.23 [1.08–1.39]	0.002
No	12899	4.77	0.82 [0.72–0.92]		0.95 [0.92–0.99]		0.87 [0.65–1.02]
CAD
Yes	144	4.31	1.41 [1.28–1.68]	0.53	1.08 [0.61–1.89]	0.81	1.07 [0.74–1.38]	0.62
No	12879	4.76	0.73 [0.64–0.84]		0.96 [0.92–0.99]		0.93 [0.86–1.16]
CVD
Yes	202	4.14	1.15 [1.01–1.31]	0.24	0.84 [0.59–1.18]	0.56	0.91 [0.72–1.26]	0.39
No	12821	4.77	0.9 [0.82–0.99]		0.96 [0.92–1.00]		1.11 [1.0–1.22]
Cardiovascular medication use
Yes	184	3.73	1.16 [0.98–1.41]	0.39	1.05 [0.81–1.34]	0.43	1.13 [1.03–1.24]	0.11
No	7993	4.78	0.89 [0.81–0.97]		0.96 [0.92–0.99]		0.89 [0.69–1.09]

Analyses adjusted for age, sex, race, ethnicity, body mass index, diabetes, hypertension, hyperlipidemia, CHF, CAD, and CVD.