Table 7.

Effect of compounds 3b, 3d, 3g and 3h on insulin, urea, creatinine, lipid profiles, HDL, LDL and VLDL levels in control and Alloxan induced diabetic rats in serum or plasma on Day 15.

Compound	Insulin (μIU/mL)	Urea (mg/dL)	Creatinine (mg/dL)	Total cholesterol (mg/dL)	Triglyceride (mg/dL)	Free fatty acids (mg/dL)	HDL-cholesterol (mg/dL)	LDL-cholesterol (mg/dL)	VLDL-cholesterol (mg/dL)
Control	16.3 ± 0.68	17.7 ± 0.2	0.71 ± 0.12	87.16 ± 6.12	13.29 ± 1.08	65.21 ± 4.12	45.16 ± 3.61	23.67 ± 1.67	19.72 ± 1.21
Diabetic control	6.9 ± 0.26	37.2 ± 1.6	1.21 ± 0.16	258.13 ± 19.98	45.17 ± 3.11	132.22 ± 9.92	22.68 ± 1.81	79.66 ± 4.95	47.51 ± 3.79
Diabetic + Glibenclamide (500 μg/kg)	11.3 ± 0.12	20.1 ± 0.98	0.78 ± 0.32	80 ± 0.26	28.60 ± 1.35	68.21 ± 4.12	22.30 ± 1.52	25.67 ± 1.67	20.50 ± 0.25
Diabetic + sample 3b (35 mg/kg bw)	10.3 ± 0.51	29.4 ± 1.6	0.96 ± 0.27	91.32 ± 7.12	16.72 ± 1.62	59.65 ± 5.16	41.67 ± 3.05	41.56 ± 4.12	28.91 ± 2.07
Diabetic + sample 3b (70 mg/kg bw)	14.3 ± 0.26	21.1 ± 2.5	0.85 ± 0.19	85.65 ± 7.73	18.94 ± 1.92	64.12 ± 7.07	40.12 ± 3.01	32.14 ± 2.71	25.71 ± 1.86
Diabetic + sample 3d (35 mg/kg bw)	12.3 ± 0.21	27.4 ± 0.25	0.86 ± 0.32	95.26 ± 0.50	36.60 ± 1.85	70.65 ± 2.56	35.67 ± 2.12	40.21 ± 1.56	19.38 ± 0.25
Diabetic + sample 3d (70 mg/kg bw)	16.3 ± 0.46	19.1 ± 1.06	0.65 ± 0.26	90.23 ± 1.63	58.40 ± 2.05	85.12 ± 1.76	40.12 ± 1.52	35.14 ± 1.27	14.97 ± 0.72
Diabetic + sample 3g (35 mg/kg bw)	10.5 ± 0.12	20.1 ± 0.98	0.68 ± 0.32	95.26 ± 0.50	46.60 ± 1.55	69.65 ± 1.56	38.67 ± 2.32	38.21 ± 1.32	20.50 ± 0.25
Diabetic + sample 3g (70 mg/kg bw)	15.3 ± 0.36	25.4 ± 0.32	0.89 ± 0.23	90.23 ± 1.63	58.40 ± 2.05	83.23 ± 1.26	42.12 ± 2.01	35.14 ± 1.25	16.23 ± 0.34
Diabetic + sample 3h (35 mg/kg bw)	10.3 ± 1.32	29.4 ± 1.23	0.96 ± 0.32	91.26 ± 0.50	45.60 ± 1.25	62.65 ± 1.56	35.67 ± 1.32	40.21 ± 0.26	22.30 ± 0.42
Diabetic + sample 3h (70 mg/kg bw)	12.3 ± 2.26	22.1 ± 2.47	0.78 ± 0.23	102.23 ± 1.63	50.40 ± 1.85	72.23 ± 1.26	45.12 ± 0.26	32.14 ± 1.32	18.52 ± 0.26