Table 3.
Compound | Curative Activity (%) a | Protection Activity (%) a | Inactivation Activity (%) a |
---|---|---|---|
4a | 29.3 ± 1.3 | 40.1 ± 2.5 | 71.3 ± 3.1 |
4b | 23.6 ± 2.2 | 38.9 ± 2.9 | 65.2 ± 2.5 |
4c | 37.9 ± 3.7 | 43.4 ± 3.1 | 61.5 ± 2.2 |
4d | 18.5 ± 1.8 | 33.6 ± 2.1 | 51.2 ± 3.4 |
4e | 55.9 ± 1.8 | 42.3 ± 1.1 | 79.6 ± 4.2 |
4f | 50.2 ± 2.7 | 46.6 ± 2.3 | 62.5 ± 1.9 |
4g | 39.8 ± 2.5 | 48.5 ± 2.7 | 66.7 ± 2.2 |
4h | 39.8 ± 2.5 | 36.2 ± 2.2 | 62.1 ±1.9 |
4i | 37.3 ± 2.5 | 35.6 ± 2.1 | 51.8 ± 1.1 |
4j | 40.6 ± 3.7 | 45.9 ± 1.6 | 79.1± 2.5 |
4k | 26.4 ± 2.3 | 35.6 ± 1.9 | 49.9± 3.6 |
4l | 29.7 ± 1.1 | 43.5 ± 2.5 | 66.5 ± 2.0 |
4m | 28.5 ± 2.3 | 42.2 ± 1.4 | 68.9 ± 2.8 |
4n | 18.9 ± 2.9 | 25.4 ± 1.7 | 46.2 ± 0.9 |
4o | 31.8 ± 2.8 | 49.9 ± 1.9 | 58.2 ± 3.2 |
4p | 29.5 ± 1.4 | 38.5 ± 2.1 | 59.8 ± 1.9 |
4q | 44.5 ± 1.8 | 48.1 ± 2.4 | 43.9 ± 1.2 |
4r | 26.4 ± 2.2 | 40.5 ± 1.9 | 42.5 ± 2.8 |
4s | 41.0 ± 1.7 | 54.7 ± 2.4 | 78.5 ± 1.9 |
4t | 34.8 ± 2.3 | 48.1 ± 1.6 | 69.5 ± 2.0 |
Ribavirin b | 36.8 ± 1.6 | 47.9 ± 2.7 | 71.2 ± 1.7 |
a Average of three replicates, at 500 μg/mL. b A commercial antiviral agent.