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. 2017 Apr 10;22(4):607. doi: 10.3390/molecules22040607

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) The predicted epitopes of DENV2 NS1 protein to antibody 1H7.4 are highlighted in lower case and colored magenta in the protein sequence. The peptides identified as binders using the sequence search only are shown in lower case. The selection criteria based on their surface exposure and secondary structure is described in detail in the supplementary section (Figure S1). The epitope LD2 is highlighted with underline; (B) Backbone presentation of the dimer form of DENV2 NS1 protein showing the predicted epitopes in magenta; (C) Surface presentation of the dimer form of DENV2 NS1 protein showing the predicted epitopes in magenta.