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Sequence alignment of DENV serotypes (1–4) with the six (1–6) epitopes for the recognition of antibody 1H7.4. The boxes show the five epitopes that are conserved across the DENV1–4 (coloured in yellow/green), and the also the critical epitope responsible for the selectivity of 1H7.4 against the serotype DENV2 (colored in red). The epitope LD2 is highlighted with underline.
