Table 1.
Groups | Dosage (mg/kg) | Body Weights (g) | Organ Indices (mg/g, ×100) | |||
---|---|---|---|---|---|---|
Initial | Final | Liver | Spleen | Kidney | ||
Normal | - | 28.92 ± 1.12 | 28.95 ± 2.13 | 5.71 ± 0.87 | 0.43 ± 0.06 | 1.65 ± 0.18 |
APAP | - | 28.74 ± 1.36 | 27.02 ± 1.26 | 7.30 ± 0.78 ** | 0.53 ± 0.09 * | 1.54 ± 0.35 |
APAP + BG | 300 | 28.76 ± 1.54 | 28.78 ± 1.62 | 4.95 ± 0.62 ## | 0.44 ± 0.03 # | 1.47 ± 0.12 |
APAP + BG | 600 | 28.81 ± 1.79 | 28.53 ± 1.71 | 5.02 ± 0.35 ## | 0.33 ± 0.05 ## | 1.45 ± 0.13 |
Values are expressed as the mean ± S.D., n = 8; * p < 0.05, ** p < 0.01 vs. normal group; # p < 0.05, ## p < 0.01 vs. APAP group.