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. 2018 Sep 14;9(72):33634–33647. doi: 10.18632/oncotarget.25950

Figure 5. Elevated levels of secreted LIF negatively correlates with lymphocyte infiltration in human OAC pre-treatment biopsies.

Figure 5

(A) CorrPlot illustrating the correlation values of secreted LIF from OAC treatment naïve biopsies cultured ex-vivo to patient clinical characteristics (stage of differentiation, tumour stage, nodal status and BMI) and percentage tumour stroma immune cell infiltrations (neutrophils, eosinophils, lymphocytes and plasma cells). Blue indicates a positive correlation, red negative correlation, (n=6) (B) Table showing Correlation values of secreted LIF to patient clinical characteristics and immune cell infiltrate (n=6). Spearman correlation to LIF secretions where Spearman r 0.4-0.59 moderate, 0.6-0.79 strong and 0.8-1 very strong.*p<0.05.