Table 2.
Associations between insight and activation or connectivity during emotion regulation.
Hemisphere | k voxels | MNI coordinates |
Z | |||
---|---|---|---|---|---|---|
x | y | z | ||||
Activation | ||||||
Clinical insight | ||||||
Suppression > attend negative and SAI-E relabeling of symptoms | ||||||
Positive correlation | ||||||
Caudate, putamen, thalamus, insula | L | 211 | −26 | 0 | 10 | 4.61 |
−24 | −6 | 16 | 4.14 | |||
−16 | −8 | 22 | 4.04 | |||
Insula, caudate | R | 251 | 22 | −16 | 20 | 4.59 |
36 | −24 | 24 | 3.91 | |||
32 | −32 | 20 | 3.87 | |||
Precentral gyrus, postcentral gyrus | R | 162 | 28 | −32 | 68 | 4.12 |
34 | −20 | 62 | 4.02 | |||
20 | −24 | 64 | 3.63 | |||
Superior occipital gyrus, cuneus | L | 228 | −14 | −82 | 42 | 4.11 |
−22 | −82 | 30 | 4.09 | |||
−28 | −72 | 18 | 3.67 | |||
Middle occipital gyrus, superior occipital gyrus, cuneus | R | 209 | 28 | −76 | 30 | 3.83 |
14 | −78 | 28 | 3.74 | |||
20 | −84 | 26 | 3.52 | |||
Cognitive insight | ||||||
Suppression > attend negative and BCIS self-reflection | ||||||
Positive correlation | ||||||
Precentral gyrus, postcentral gyrus | L | 113 | −34 | −18 | 44 | 4.85 |
−46 | −12 | 38 | 3.49 | |||
Middle cingulate gyrus | L | 121 | −12 | −6 | 40 | 4.38 |
−10 | 2 | 34 | 3.73 | |||
−6 | −14 | 40 | 3.68 | |||
Precentral gyrus, postcentral gyrus | R | 224 | 46 | −16 | 36 | 4.32 |
36 | −18 | 40 | 4.09 | |||
48 | −4 | 32 | 4.05 | |||
Connectivity | ||||||
Clinical insight | ||||||
Suppression > attend negative and SAI-E subtotal (seed: midline medial frontal gyrus) | ||||||
Negative correlation | ||||||
Middle occipital gyrus (lingual gyrus, fusiform gyrus) | R | 104 | 30 | −80 | 0 | 4.16 |
28 | −68 | 2 | 3.73 | |||
26 | −86 | −8 | 3.45 |
All results of regression analyses are shown with an initial threshold of p < 0.001 (uncorrected) and cluster-level FWE-corrected p < 0.05.
Abbreviations: L = left; R = right.