Fig. 2.
Effect of IL-12p35 KO on DOX-induced cardiac injury. (A) Body weight was measured in each group at different times; N = 8 in each group. (B) Heart weight was measured at the end of the fifth day in the four groups; N = 8 in each group. (C) Heart sections were obtained and stained with HE. The vacuolated cardiomyocytes were quantified (400×); N = 6 in each group. Serum LDH (D) and CK-MB (F) levels were assessed; N = 8 in each group. Heart LDH (E) and CK-MB (G) levels were detected; N = 4 in each group. *P < 0.05 vs. the control group, and #P < 0.05 vs. the DOX group.