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Evaluation of LV function by echocardiography and hemodynamic data in each group. HR (A), LVEF (B), and FS (C) were evaluated by echocardiography in the control, p35 KO, DOX and DOX + p35 KO groups. Positive and negative dP/dt max (D, E), LVSP (F) and LVEDP (G) were assessed by hemodynamic data in the four groups; N = 8 in each group. *P < 0.05 vs. the control group, and #P < 0.05 vs. the DOX group.
