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Effect of IL-12p35 KO on DOX-induced myocardial apoptosis. (A). Representative images and quantification of Bax, Bcl2, Cyto C, Cle-cas9, Cle-cas3 and GAPDH by western blotting in the control, p35 KO, DOX and DOX + p35 KO groups. (B). Representative images of TUNEL staining and the quantitative results in each group (400×); N = 6 in each group. *P < 0.05 vs. the control group, and #P < 0.05 vs. the DOX group.
