ITGAE demarcates CD8+ TIL in normal colorectal epithelial tissue.
(a) Representative image of normal colorectal epithelial tissue stained with DAPI (DNA, blue), anti-CD8 (green), anti-ITGAE (red) and double CD8/ITGAE+ (orange). (b) Representative images of CD8+ and ITGAE+ cells in the epithelial areas. (c) Representative image of tissue from a colorectal cancer stained with DAPI (DNA, blue), anti-CD3 (green), anti-ITGAE (red).