Table 4.
Significant factors for COPD diagnosis in all subjects
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Age (years) | 1.11 | (1.09,1.13) | < 0.001 | 1.10 | (1.07,1.13) | < 0.001 |
| Male | 1.02 | (0.49,2.13) | 0.954 | |||
| Height (cm) | 0.95 | (0.92,0.97) | < 0.001 | 1.01 | (0.97,1.05) | 0.786 |
| Weight (kg) | 0.93 | (0.91,0.95) | < 0.001 | 0.98 | (0.95,1.01) | 0.143 |
| Smoking history | ||||||
| Current smoking | 0.92 | (0.65,1.3) | 0.631 | |||
| Pack-years | 1.02 | (1.01,1.03) | < 0.001 | 1.01 | (1.00,1.02) | 0.059 |
| Co-morbidity | ||||||
| Pulmonary tuberculosis | 2.78 | (1.79,4.31) | < 0.001 | 1.17 | (0.66,2.10) | 0.587 |
| Asthma | 13.11 | (8.27,20.79) | < 0.001 | 1.88 | (0.97,3.64) | 0.060 |
| Lung function test | ||||||
| FVC % predicted | 0.95 | (0.94,0.97) | < 0.001 | 1.03 | (1.01,1.05) | 0.006 |
| FEV1% predicted | 0.93 | (0.92,0.94) | < 0.001 | 0.95 | (0.93,0.96) | < 0.001 |
| FEV1/FVC | 0.001 | (0.001,0.001) | < 0.001 | |||
| Self-reported respiratory symptoms | ||||||
| Cough for more than 3 months | 37.80 | (15.55,91.87) | < 0.001 | 2.40 | (0.24,24.32) | 0.458 |
| Sputum for more than 3 months | 17.78 | (7.81,40.52) | < 0.001 | 0.48 | (0.02,10.90) | 0.647 |
| Dyspnea | 25.49 | (13.68,47.49) | < 0.001 | 3.07 | (1.23,7.68) | 0.017 |
| Wheezing | 7.83 | (5.42,11.31) | < 0.001 | 2.90 | (1.76,4.78) | < 0.001 |
| Chronic bronchitis | 23.21 | (10.67,50.5) | < 0.001 | 2.76 | (0.07,109.05) | 0.588 |
Statistically significant data are presented as bold
COPD chronic obstructive pulmonary disease, FEV1 forced expiratory volume for 1 s, FVC forced vital capacity, OR odds ratio, CI confidence interval