Table 6.
Significant factors for COPD diagnosis in PRISm
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Age (years) | 1.14 | (1.08, 1.21) | < 0.001 | 1.14 | (1.05, 1.24) | 0.002 |
| Male | ||||||
| Height (cm) | 0.93 | (0.87, 0.99) | 0.025 | 1.03 | (0.92, 1.16) | 0.564 |
| Weight (kg) | 0.94 | (0.9, 0.99) | 0.013 | 0.95 | (0.89, 1.02) | 0.153 |
| Smoking history | ||||||
| Current smoking | 0.61 | (0.22, 1.66) | 0.329 | |||
| Pack-years | 1.01 | (0.99, 1.03) | 0.490 | |||
| Co-morbidity | ||||||
| Pulmonary tuberculosis | 0.92 | (0.12, 7.35) | 0.940 | |||
| Asthma | 8.67 | (2.41, 31.23) | 0.001 | 5.87 | (0.94, 36.56) | 0.058 |
| Lung function test | ||||||
| FVC % predicted | 0.93 | (0.89, 0.97) | 0.001 | 1.01 | (0.95, 1.09) | 0.694 |
| FEV1% predicted | 0.95 | (0.9, 1.01) | 0.071 | |||
| FEV1/FVC | 0.001 | (0.001, 35.7) | 0.183 | |||
| Self-reported respiratory symptoms | ||||||
| Cough for more than 3 months | ||||||
| Sputum for more than 3 months | ||||||
| Dyspnea | 42.29 | (3.61, 494.74) | 0.003 | 8.88 | (0.65, 121.7) | 0.102 |
| Wheezing | 5.15 | (1.75, 15.14) | 0.003 | 4.56 | (1.08, 19.35) | 0.040 |
| Chronic bronchitis | ||||||
Statistically significant data are presented as bold
COPD chronic obstructive pulmonary disease, PRISm preserved ratio impaired spirometry, FEV1 forced expiratory volume for 1 s, FVC forced vital capacity, OR odds ratio, CI confidence interval