. LMK-235 upregulated BCLAF1 expression. (A) DLBCL cell lines OCI-LY10 were treated with different concentrations of LMK-235 (0, 0.5, 1.0, 1.5, 2.0, 2.5 μmol / l)for 24 hours or vehicle alone, and the mRNA expression of BCLAF1 was analyzed with q-PCR. Each value represents the average of three independent experiments. (B) DLBCL cell lines were treated with the indicated concentrations of LMK-235 at different times. The mRNA expression of BCLAF1 was analyzed with q-PCR. (C) DLBCL cell lines were treated with LMK-235, and the relative protein expression of the BCLAF1 were detected by Western blot. All experiments were performed three times. The data is expressed as mean ± SD. * P <0.05 compared with the control group.