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PARP1 inhibitors kill ovarian and breast cancer cells. a. Tumor cells were treated with vehicle control or with niraparib (2.0 μM). After 12h and 24h, cells were isolated and viability determined by trypan blue exclusion (n = 3 +/- SD). b. Tumor cells were treated with vehicle control or with olaparib (2.0 μM) or with cobimetinib (100 nM). After 12h and 24h, cells were isolated and viability determined by trypan blue exclusion (n = 3 +/- SD).
