AdPC	prostate adenocarcinoma
NEPC	neuroendocrine prostate cancer
SRRM4	serine/arginine repetitive matrix 4 (also known as nSR100)
SOX2	sex determining region Y-box 2
CRPC	castration-resistant prostate cancer
AR	androgen receptor
CRPC-Ad	castration-resistant prostate adenocarcinoma
t-NEPC	treatment-induced neuroendocrine prostate cancer
TP53	tumor protein p53
RB1	retinoblastoma transcriptional corepressor 1
PTEN	phosphatase and tensin homolog
NE	neuroendocrine
SC	stem cell
REST	RE1 silencing transcription factor
EZH2	enhancer of zeste 2 polycomb repressive complex 2
LnNE	SRRM4-transduced LNCaP cell-derived neuroendocrine prostate cancer model
PSA	prostate-specific antigen
VPC	Vancouver Prostate Centre
RISH	RNA in situ hybridization
IHC	immunohistochemistry
E-Cad	E-cadherin
SYP	synaptophysin
BrdU	bromodeoxyuridine
Doce	docetaxel
CPT	camptothecin
GSEA	gene set enrichment analysis
PDX	patient-derived xenograft
GEMM	genetically engineered mouse model
GEO	gene expression omnibus
WT	wild-type
SKO	single knock-out
DKO	double knock-out
TKO	triple knock-out
LE	luminal epithelial
c-PARP	cleaved poly(ADP-ribose) polymerase
GO	gene ontology
DuNE	SRRM4-transduced DU145 cell-derived neuroendocrine prostate cancer model