Table 2.
LT4 supplementation and pregnancy outcomes following IVF/ICSI, in women with SCH and/or TAI, without combining the study by Kim et al.
| Subgroup | Number of studies | Number of patients | Statistical method | Effect size | I2 (%) |
|---|---|---|---|---|---|
| Clinical pregnancy | 3 | 723 | RR (Random, 95% CI) | 1.49 (0.75, 2.94) | 90 |
| Live birth | 3 | 723 | RR (Random, 95% CI) | 2.11 (0.76, 5.84) | 88 |
| Miscarriage | 3 | 723 | RR (Random, 95% CI) | 0.53 (0.35, 0.82) | 0 |
| Preterm birth | 1 | 567 | RR (Random, 95% CI) | 1.13 (0.65, 1.96) | N/A |
SCH subclinical hypothyroidism; TAI thyroid autoimmunity; RR risk ratio; CI confidence interval; N/A not available