Fig. 1.

Expression levels of MLK7-AS1 in ovarian cancer tissues, serum, and cell lines. (a) Expression levels of MLK7-AS1 were upregulated in ovarian cancer tissues compared with the adjacent non-tumor tissues (n = 45). (b) MLK7-AS1 expressions were upregulated in ovarian cancer serum samples (n = 45) compared with the healthy controls (n = 45). (c) Correlation of MLK7-AS1 expression levels in ovarian cancer tissue and serum (n = 45). (d) Expression levels of MLK7-AS1 in ovarian cancer cell lines. (e) Patients with high MLK7-AS1 expression had poorer overall survival (OS) rates than those with low MLK7-AS1 expression (n = 45). (F) MLK7-AS1 expression was an independent prognostic indicator for OS in ovarian cancer patients. (g) ROC curve analysis was applied to determine the diagnostic value of MLK7-AS1. (h) Serum MLK7-AS1 expression levels were downregulated in postoperative samples (n = 45). Data presented as the mean ± standard deviation (SD) of three independent experiments. *P < 0.05, **P < 0.01