Table 2.

Univariate and multivariable Cox proportional hazard regression analyses for overall survival

Variable	Univariate analysis				Multivariate analysis
	HR	95% CI		P-value	HR	95% CI		P-value
Depth of invasion	2.012	1.802	2.312	0.021*	2.089	1.818	2.359	0.004*
Lymph node metastasis	1.910	1.610	2.016	0.030*	2.000	1.760	2.240	0.023*
Distant metastasis	1.524	1.366	1.681	0.014*
TNM stage	1.934	1.689	2.234	< 0.001*	2.200	1.846	2.554	< 0.001*
MLK7-AS1	2.689	2.329	3.081	0.001*	2.975	2.554	3.396	0.017*

HR relative risk, 95% CI:95% confidence interval. *Statistically significant P < 0.05