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. 2018 Sep 21;9:3848. doi: 10.1038/s41467-018-06377-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — A proposed model for sister chromatid cohesion by RSF1. In our model, Tip60 contributes to maintaining H2A-K118ac at chromosome arms and RSF1-bound HDAC1 at centromeres counteracts it, allowing the phosphorylation of H2A at T120 by Bub1. Green circle represents H2A-T120 and red circle is its phosphorylated form (H2A-pT120). Yellow circle represents acetylation of H2A at Lys 118 (H2A-K118ac)