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. 2018 Sep 21;8:14227. doi: 10.1038/s41598-018-31986-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation analysis of the positive and negative regulation of differential microRNA-mRNA expression. The abscissa is the log2 value of the multiple difference of target genes, and the longitudinal coordinate is the log2 value of the multiple difference of microRNAs. The red dashed line is 1.5 times the difference of the ascending line. The blue dashed line is 1.5 times the difference of the demarcation line.