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. 2018 Sep 21;8:198. doi: 10.1038/s41398-018-0227-2

Table 2.

Monoamine oxidase A distribution volume

ROI SAD HC
PET1 (fall/winter before BLT/placebo)
 Frontal pole 18.65 ± 4.49 18.61 ± 4.05
 Temporal pole 18.58 ± 4.04 17.81 ± 3.82
 Anterior cingulate gyrus 21.48 ± 4.76 21.08 ± 4.94
 Posterior cingulate gyrus 21.30 ± 5.14 21.30 ± 4.52
 Thalamus 24.58 ± 5.88 25.21 ± 6.35
 Caudate 15.67 ± 3.95 15.44 ± 3.15
 Putamen 21.36 ± 5.15 21.06 ± 4.55
 Hippocampus 20.96 ± 5.02 20.70 ± 4.60
 Midbrain 24.71 ± 5.79 24.39 ± 6.05
PET2 (fall/winter after BLT)
 Frontal pole 16.81 ± 5.14 18.00 ± 5.13
 Temporal pole 16.99 ± 5.44 17.25 ± 5.33
 Anterior cingulate gyrus 19.65 ± 5.97 20.04 ± 6.56
 Posterior cingulate gyrus 19.47 ± 6.22 20.07 ± 6.36
 Thalamus 22.46 ± 6.88 23.84 ± 6.02
 Caudate 14.39 ± 4.84 14.42 ± 3.94
 Putamen 19.69 ± 5.97 20.44 ± 5.76
 Hippocampus 18.95 ± 6.00 19.80 ± 5.69
 Midbrain 22.49 ± 6.16 23.66 ± 7.17
PET2 (fall/winter after placebo)
 Frontal pole 18.89 ± 4.17 19.13 ± 3.22
 Temporal pole 18.33 ± 3.63 18.45 ± 3.77
 Anterior cingulate gyrus 21.62 ± 4.60 22.58 ± 4.63
 Posterior cingulate gyrus 21.50 ± 4.57 22.75 ± 4.08
 Thalamus 24.79 ± 5.37 26.19 ± 5.01
 Caudate 16.07 ± 4.07 16.36 ± 2.86
 Putamen 21.10 ± 4.10 21.82 ± 4.08
 Hippocampus 21.15 ± 4.42 21.73 ± 3.92
 Midbrain 24.67 ± 5.18 25.12 ± 5.26
PET3 (spring/summer)
 Frontal pole 18.67 ± 3.50 18.23 ± 3.99
 Temporal pole 18.85 ± 3.73 17.63 ± 4.16
 Anterior cingulate gyrus 22.33 ± 4.95 21.14 ± 5.41
 Posterior cingulate gyrus 21.81 ± 4.31 20.88 ± 4.91
 Thalamus 23.73 ± 4.71 24.01 ± 4.71
 Caudate 14.68 ± 2.55 14.47 ± 3.14
 Putamen 21.01 ± 3.77 20.44 ± 4.33
 Hippocampus 20.41 ± 3.39 20.18 ± 3.94
 Midbrain 25.36 ± 5.35 24.70 ±6.05

Monoamine oxidase A distribution volume (MAO-A VT) reported as mean ± SD. ROI: region of interest, SAD: seasonal affective disorder, HC: healthy controls, BLT: bright light therapy, PET: positron emission tomography