Table 2.

Monoamine oxidase A distribution volume

ROI	SAD	HC
PET1 (fall/winter before BLT/placebo)
Frontal pole	18.65 ± 4.49	18.61 ± 4.05
Temporal pole	18.58 ± 4.04	17.81 ± 3.82
Anterior cingulate gyrus	21.48 ± 4.76	21.08 ± 4.94
Posterior cingulate gyrus	21.30 ± 5.14	21.30 ± 4.52
Thalamus	24.58 ± 5.88	25.21 ± 6.35
Caudate	15.67 ± 3.95	15.44 ± 3.15
Putamen	21.36 ± 5.15	21.06 ± 4.55
Hippocampus	20.96 ± 5.02	20.70 ± 4.60
Midbrain	24.71 ± 5.79	24.39 ± 6.05
PET2 (fall/winter after BLT)
Frontal pole	16.81 ± 5.14	18.00 ± 5.13
Temporal pole	16.99 ± 5.44	17.25 ± 5.33
Anterior cingulate gyrus	19.65 ± 5.97	20.04 ± 6.56
Posterior cingulate gyrus	19.47 ± 6.22	20.07 ± 6.36
Thalamus	22.46 ± 6.88	23.84 ± 6.02
Caudate	14.39 ± 4.84	14.42 ± 3.94
Putamen	19.69 ± 5.97	20.44 ± 5.76
Hippocampus	18.95 ± 6.00	19.80 ± 5.69
Midbrain	22.49 ± 6.16	23.66 ± 7.17
PET2 (fall/winter after placebo)
Frontal pole	18.89 ± 4.17	19.13 ± 3.22
Temporal pole	18.33 ± 3.63	18.45 ± 3.77
Anterior cingulate gyrus	21.62 ± 4.60	22.58 ± 4.63
Posterior cingulate gyrus	21.50 ± 4.57	22.75 ± 4.08
Thalamus	24.79 ± 5.37	26.19 ± 5.01
Caudate	16.07 ± 4.07	16.36 ± 2.86
Putamen	21.10 ± 4.10	21.82 ± 4.08
Hippocampus	21.15 ± 4.42	21.73 ± 3.92
Midbrain	24.67 ± 5.18	25.12 ± 5.26
PET3 (spring/summer)
Frontal pole	18.67 ± 3.50	18.23 ± 3.99
Temporal pole	18.85 ± 3.73	17.63 ± 4.16
Anterior cingulate gyrus	22.33 ± 4.95	21.14 ± 5.41
Posterior cingulate gyrus	21.81 ± 4.31	20.88 ± 4.91
Thalamus	23.73 ± 4.71	24.01 ± 4.71
Caudate	14.68 ± 2.55	14.47 ± 3.14
Putamen	21.01 ± 3.77	20.44 ± 4.33
Hippocampus	20.41 ± 3.39	20.18 ± 3.94
Midbrain	25.36 ± 5.35	24.70 ±6.05

Monoamine oxidase A distribution volume (MAO-A V_T) reported as mean ± SD. ROI: region of interest, SAD: seasonal affective disorder, HC: healthy controls, BLT: bright light therapy, PET: positron emission tomography