Figure 8.

Microbiota associated with Rheumatoid arthritis and Osteoarthritis. (A) Relative abundance of the top 76 most different OTUs across taxonomic groups (P < 0.1, by Wilcoxon rank sum test). Abundance profiles were transformed into Z-scores by subtracting the average abundance and dividing the standard deviation of all samples. Z score was negative (shown in blue) when the row abundance was lower than the mean. *P < 0.01; **P < 0.05. (B) Receiver operating characteristic curves for STRA and STOA groups, determined using OTU markers, sequencing datasets, and a supervised learning approach with random Forest algorithm. (C) Receiver operating characteristic curves for SFRA and SFOA groups, determined using OTU markers, sequencing datasets, and a supervised learning approach with random Forest algorithm.