Table 3.
Summary of carboxyethylation HEBM reactions (numbering is identical with Table 1).
| No | NaOH (g (mole)) | Reagent (g (mole)) | Milling Time (h) | Final Temp. (°C) | Yield (g (%)) | DS | Residual Reagent 1 (%) |
|---|---|---|---|---|---|---|---|
| 5 | 0.24 (0.006) | 0.64 (0.005) 2 | 2.5 | 67 | 0.72 (50.3) | 3.0–3.3 | ≈1.0 |
| 6 | 0.24 (0.006) | 0.64 (0.005) 2,3 | 3.5 | 70 | 0.42 (29.6) | 2.8–3.2 | <1.0 |
| 7 | 0.24 (0.006) | 0.54 (0.005) 4 | 3.5 | 93 | 0.74 5 (52.1) | 2.8–3.1 | <11 |
1 Or reagent derived by-product; 2n-butyl acrylate; 3 dried βCD; 4 reaction of sodium acrylate; 5 corrected with sodium acrylate content.