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. 2018 Sep 24;9(10):986. doi: 10.1038/s41419-018-1040-9

Fig. 3. MCL-1 expression level correlates with sensitivity of NSCLC to MCL-1 and BCL-xL inhibition.

Fig. 3

Expression levels of BCL-2, BCL-xL, BIM, BID, PUMA, and MCL-1 were quantified using the Image Studio Ver 5.0 software. The level for each protein in SK-LU-1 cells was set as 1, and relative expression levels in other cells was calculated by comparing to SK-LU-1 cells. af The percentages of apoptotic cells induced by knockdown of MCL-1 combined with ABT-263 were plotted against relative expression levels of individual proteins in the NSCLC cells. The non-parametric one-tailed Spearman’s correlation test was applied to perform statistical analysis