Effect of stilbenoids on arterial wall component stiffness. (A) In mesenteric arteries, the elastic modulus-stress curve of untreated SHHF is unchanged relative to untreated SD, and this is reflected by (C) similar slopes of the elastic modulus-stress curve between SD and SHHF arteries, in the presence and absence of stilbenoid treatment; (B) In middle cerebral arteries, the elastic modulus-stress curve for untreated SHHF is shifted leftward, and this is reflected by (D) the statistically significant increase in slope. This was attenuated by 8-week treatment with resveratrol, pterostilbene, and gnetol (2.5 mg/kg/day). n = 4–8. * p < 0.05 and ** p < 0.01 vs. untreated SD. †
p < 0.05 and ††
p < 0.01 vs. untreated SHHF.