Table 1.2.
Predictive variables for OS and PFS of 212 patients with HCC by univariate survival analysis (SYSUCC)
| Variable | OS (months) | PFS (months) | |||
|---|---|---|---|---|---|
| Cases | HR(95% CI) | p value | HR(95% CI) | p value* | |
| Age(years) | 0.627 | 0.668 | |||
| ≤47.9# | 105 | 1.0 | 1.0 | ||
| >47.9 | 107 | 1.092 (0.77–1.542) | 1.061 (0.72–1.603) | ||
| Gender | 0.045 | 0.058 | |||
| Male | 174 | 1.651 (1.012–2.688) | 1.352 (0.083–2.125) | ||
| Female | 38 | 1.0 | 1.0 | ||
| Hepatitis history | 0.810 | 0.524 | |||
| Yes | 164 | 1.053 (0.692–1.602) | 1.072 (0.059–1.633) | ||
| No | 48 | 1.0 | 1.0 | ||
| AFP(ng/ml) | 0.000 | 0.000 | |||
| ≤20 | 67 | 1.0 | 1.0 | ||
| >20 | 145 | 2.262 (1.490–3.434) | 3.389 (2.157–4.886) | ||
| Tumor size(cm) | 0.000 | 0.002 | |||
| ≤5 | 59 | 1.0 | 1.0 | ||
| >5 | 153 | 6.295 (3.688–10.747) | 3.963 (2.597–5.559) | ||
| Tumor multiplicity | 0.000 | 0.001 | |||
| Single | 128 | 1.0 | 1.0 | ||
| Multiple | 84 | 3.480 (2.429–4.987) | 3.669 (2.582–5.139) | ||
| Stage | 0.000 | 0.000 | |||
| I–II | 88 | 1.0 | 1.0 | ||
| III–IV | 124 | 5.393 (3.525–8.252) | 4.847 (3.331–9.147) | ||
| Vascular invasion | 0.000 | 0.000 | |||
| Yes | 108 | 4.923 (3.331–7.322) | 4.336 (3.139–6.736) | ||
| No | 104 | 1.0 | 1.0 | ||
| PGAM5 expression | 0.016 | 0.003 | |||
| Low | 100 | 1.0 | 1.0 | ||
| High | 112 | 3.165 (2.785–6.133) | 4.391 (2.336–8.461) | ||
#mean age
*Log-rank test