Table 2.2.
Multivariate Cox regression analysis for OS and PFS in patients with HCC (SYSUCC)
| Variable | OS | PFS | ||||
|---|---|---|---|---|---|---|
| HR | 95%Cl | p value | HR | 95%Cl | p value | |
| AFP, ng/ml (≤20 vs >20) | 1.452 | 1.018–2.069 | 0.041 | 2.316 | 1.527–3.663 | 0.025 |
| Tumor size, cm (≤5 vs >5) | 1.621 | 0.888–3.053 | 0.165 | 1.337 | 0.726–2.176 | 0.216 |
| Tumor multiplicity(single vs multiple) | 1.736 | 0.969–42.112 | 0.064 | 2.225 | 1.362–3.681 | 0.026 |
| Stage (I–II vs III–IV) | 1.565 | 0.908–2.456 | 0.132 | 1.669 | 1.315–2.538 | 0.043 |
| Vascular invasion | 1.901 | 1.234–2.929 | 0.004 | 2.013 | 1.662–3.269 | 0.026 |
| PGAM5 expression(positive vs negative) | 1.862 | 1.307–3.882 | 0.007 | 2.016 | 1.623–3.669 | 0.003 |
HR hazard ratio, CI confidence interval