Table 4.

Performance comparison of PredHS2 and other existing methods on the independent test dataset.

Method	TP	TN	FP	FN	ACC	SPE	PRE	SEN	F1	MCC
PredHS2	30	80	7	9	0.87	0.92	0.81	0.77	0.79	0.70
iPPHOT	31	51	36	8	0.65	0.59	0.46	0.79	0.58	0.35
HEP	32	68	21	6	0.79	0.76	0.60	0.84	0.70	0.56
PredHS-SVM	23	81	6	16	0.83	0.93	0.79	0.59	0.68	0.57
APIS	28	67	21	11	0.75	0.76	0.57	0.72	0.64	0.45
Robetta	12	80	11	24	0.72	0.88	0.52	0.33	0.41	0.25
FOLDEF	10	78	11	28	0.69	0.88	0.48	0.26	0.34	0.17
KFC	12	75	12	27	0.69	0.85	0.48	0.31	0.38	0.19
MINERVA	17	79	9	22	0.76	0.9	0.65	0.44	0.52	0.38
KFC2a	29	64	24	10	0.73	0.73	0.55	0.74	0.63	0.44
KFC2b	21	77	12	17	0.77	0.87	0.65	0.55	0.60	0.44