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. 2018 Sep 25;13(9):e0204336. doi: 10.1371/journal.pone.0204336

Table 2. Biochemical parameters of liver function in healthy and cholestatic rats.

Healthy Cholestatic
Vehicle DEX
Albumin (g/L) 37.2 ± 2.2 30.7 ± 4.3 40.5 ± 4.3*,##
ALKP (U/L) 184.7± 15.3 340.7 ± 73.3* 247.6 ± 117.8
ALT (U/L) 41.8 ± 14.3 149.7 ± 39.1*** 61.2 ± 25.8 ###
AST (U/L) 83.8 ± 7.5 570.7 ± 104.3*** 230.5 ± 193##
Total bilirubin (mmol/L) 1.0 ± 0.2 204.0 ± 15.0*** 66.7 ± 22.4###

Results are given as mean ± SD.

*P < 0.05,

***P < 0.001 vs healthy animals;

##P < 0.01,

###P < 0.001 vs cholestatic rats treated with vehicle.