Table 2. Biochemical parameters of liver function in healthy and cholestatic rats.
Healthy | Cholestatic | ||
---|---|---|---|
Vehicle | DEX | ||
Albumin (g/L) | 37.2 ± 2.2 | 30.7 ± 4.3 | 40.5 ± 4.3*,## |
ALKP (U/L) | 184.7± 15.3 | 340.7 ± 73.3* | 247.6 ± 117.8 |
ALT (U/L) | 41.8 ± 14.3 | 149.7 ± 39.1*** | 61.2 ± 25.8 ### |
AST (U/L) | 83.8 ± 7.5 | 570.7 ± 104.3*** | 230.5 ± 193## |
Total bilirubin (mmol/L) | 1.0 ± 0.2 | 204.0 ± 15.0*** | 66.7 ± 22.4### |
Results are given as mean ± SD.
*P < 0.05,
***P < 0.001 vs healthy animals;
##P < 0.01,
###P < 0.001 vs cholestatic rats treated with vehicle.