Table 2.
The predicted results of peptides by pharmacophore and docking.
| NO. a | Peptide Sequence | Fitvalue b | -CDOCKER ENERGY c | NO. a | Peptide Sequence | Fitvalue b | -CDOCKER ENERGY c |
|---|---|---|---|---|---|---|---|
| 1-1 | QEKQKL | none | none | 2-4 | GGAAGGAF | 0.95 | 165.39 |
| 1-2 | EKHNRL | none | none | 3-1 | GAAGGAF | 0.96 | 163.62 |
| 1-3 | QSGDQQEF | 0.97 | none | 3-2 | AAGGAF | 0.95 | 143.18 |
| 1-4 | VGQLGGAAGGAF | 0.96 | 180.40 | 3-3 | AGGAF | 0.96 | 132.88 |
| 1-5 | QQQQQQQQQQQQSL | none | none | 3-4 | GGAF | 0.96 | 119.30 |
| 1-6 | PATAHKQQQQADANMAKL | none | none | 3-5 | GAF | 0.95 | 112.38 |
| 2-1 | VGQL | none | 108.65 | 3-6 | AF | 0.23 | 99.54 |
| 2-2 | GGAAGGA | none | 137.75 | 4 | lisinopril | 0.95 | 71.22 |
| 2-3 | VGQ | none | 112.56 |
a No. 1-1 to 1-6 represented the sequence of six identified peptides; No. 2-1 to 2-4 represented the sequence of four peptides by in silico proteolysis of VGQLGGAAGGAF; No. 3-1 to 3-6 stood for the sequence of six peptides by sequential division from GGAAGGAF; b Fitvalues were the scores of pharmacophore screening; c -CDOCKER ENERGY was the scoring function of docking modelling and represented the interaction ability between ligands and receptor.