Table 2.
IC50 values of Photofrin-PDT and sinoporphyrin sodium-PDT towards human cancer cell lines and immortal keratinocyte cells (X ± SD).
| Cell Line | IC50 (μg/mL) Photofrin® | IC50 (μg/mL) Sinoporphyrin Sodium |
|---|---|---|
| U251 | 4.5 ± 1.0 | 0.5 ± 0.2 |
| HaCaT | 10 ± 1.0 | 1.4 ± 0.4 |
| BGC-823 | 1.5 ± 0.3 | 0.2 ± 0.1 |
| HepG2 | 1.4 ± 0.2 | 0.3 ± 0.2 |
| MCF-7 | 0.7 ± 0.1 | 0.08 ± 0.03 |
| H460 | 3.3 ± 0.9 | 0.6 ± 0.2 |
| ketr3 | 2.3 ± 1.0 | 0.2 ± 0.1 |
| A375 | 1.9 ± 0.2 | 0.21 ± 0.01 |
| A2780 | 1.3 ± 0.3 | 0.12 ± 0.04 |
| HCT-8 | 1.4 ± 0.7 | 0.09 ± 0.04 |
| HCT-116 | 0.3 ± 0.1 | 0.09 ± 0.02 |
| Bel7402 | 2.9 ± 0.4 | 0.8 ± 0.2 |