Table 2.
Result of isobolographic analysis showing CI of DOX in the presence of different concentrations of XN in MCF-7 cells. The CI values were calculated by CompuSyn.
| XN (μM) | DOX (μM) | Effect | CI |
|---|---|---|---|
| 2.5 | 0.15 | 0.19 | 1.89 |
| 2.5 | 0.3 | 0.22 | 2.33 |
| 2.5 | 0.625 | 0.43 | 0.97 |
| 2.5 | 1.25 | 0.49 | 1.16 |
| 2.5 | 2.5 | 0.66 | 0.71 |
| 2.5 | 5 | 0.65 | 1.38 |
| 2.5 | 10 | 0.75 | 1.21 |
| 5 | 0.15 | 0.24 | 1.87 |
| 5 | 0.3 | 0.51 | 0.63 |
| 5 | 0.625 | 0.52 | 0.80 |
| 5 | 1.25 | 0.6 | 0.76 |
| 5 | 2.5 | 0.69 | 0.69 |
| 5 | 5 | 0.69 | 1.15 |
| 5 | 10 | 0.78 | 1.01 |
| 10 | 0.15 | 0.43 | 1.30 |
| 10 | 0.3 | 0.54 | 0.94 |
| 10 | 0.625 | 0.57 | 0.98 |
| 10 | 1.25 | 0.61 | 1.03 |
| 10 | 2.5 | 0.72 | 0.77 |
| 10 | 5 | 0.71 | 1.21 |
| 10 | 10 | 0.77 | 1.26 |