Table 1.
The anticancer IC50 values of compounds using a MTT assay against HepG-2, PC-3 and HCT116 cell lines.
| Compound | HCT-116 | PC-3 | HepG-2 |
|---|---|---|---|
| IC50 (nM) ± SD | |||
| 1 | 178.1 ± 5.3 | 184.1 ± 6.3 | 509.5 ± 9.2 |
| 3 | 201.3 ± 3.8 | 210.2 ± 4.7 | 541.4 ± 7.2 |
| 7 | 120.1 ± 4.1 | 223.9 ± 6.4 | 134.5 ± 4.9 |
| 9 | 95.8 ± 3.7 | 281.8 ±3.6 | 285.1 ± 3.9 |
| 12 | 250.3 ± 5.7 | 437.4 ± 5.3 | 425.6 ± 8.6 |
| 13 | 204.6 ± 3.8 | 217.7 ± 8.1 | 581.5 ± 9.3 |
| 14 | 92.2 ± 1.8 | 120.8 ± 3.9 | 176.1 ± 2.9 |
| 15 | 204.6 ± 3.5 | 331.3 ± 9.2 | 348.5 ± 7.4 |
| 17 | 127.4 ± 5.6 | 693.9 ± 8.9 | 209.7 ± 10.1 |
| 18 | 106.3 ± 2.9 | 111.6 ± 3.8 | 334.1 ± 9.9 |
| 19 | 106.6 ± 4.2 | 9493.8 ± 20.9 | 599.0 ± 11.5 |
| Doxorubicin | 126.7 ± 8.9 | 129.7 ± 2.4 | 117.1 ± 5.8 |