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. 2017 Jan 4;22(1):71. doi: 10.3390/molecules22010071

Table 3.

Fractional inhibitory concentration (FIC) values of tested compounds in combination with metronidazole against clinical strains of H. pylori (11, 12) and control strain by standard checkerboard titration method with two-fold serial agar dilutions.

Compounds FIC Values (Index) (MIC Combination) FIC Mean
Strain Number
11 12 Control Strain
3a-MTZ 0.328 (*) 0.328 (*) 0.328 (*) 0.328 (*)
(2.5) (2.5) (2.5)
3b-MTZ 1.312 (=) 1.312 (=) 1.312 (=) 1.312 (=)
(10) (10) (10)
3c-MTZ 0.656 (+) 0.656 (+) 0.656 (+) 0.656 (+)
(5) (5) (5)
3d-MTZ 0.328 (*) 0.328 (*) 0.328 (*) 0.328 (*)
(2.5) (2.5) (2.5)
3e-MTZ 1.312 (=) 0.656 (+) 0.656 (+) 0.874 (+)
(10) (5) (5)

(*): Synergism; (+): Additive; (=): Indifferent.