Table 1.
Scavenging of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, 15-lipoxygenase (15-LO), xanthine oxidase (XO), α-glucosidase and α-amylase inhibitory activity of elderflower crude extracts. IC50 values ± standard deviation (SD) are shown.
| Elderflower Extract | DPPH (µg/mL) | 15-LO (µg/mL) | XO (µg/mL) | α-Glucosidase (µg/mL) | α-Amylase (µg/mL) |
|---|---|---|---|---|---|
| DCM | >167 | 125.9 ± 3.9 | >167 | 105 ± 5.6 | 103 ± 5.9 |
| 96% EtOH | 9.2 ± 0.9 | 17.9 ± 3.6 | 59.3 ± 6.3 | 4.8 ± 0.5 | 2.8 ± 1.1 |
| 50% EtOH | 20.2 ± 3.9 | 24.4 ± 3.1 | 79.5 ± 4.1 | 8.9 ± 1.1 | 3.1 ± 1.3 |
| 50 °C Water | 68.9 ± 2.3 | 126.6 ± 3.9 | 156.5 ± 5.3 | 78.9 ± 5.8 | 71.8 ± 4.1 |
| 100 °C Water | 32.0 ± 2.9 | 75.9 ± 6.5 | 135.6 ± 7.8 | 65.3 ± 4.6 | 66.2 ± 5.6 |
| Quercetin (control) | 2.8 ± 0.3 | 29.3 ± 1.9 | 0.7 ± 0.2 | nt | nt |
| Acarbose (control) | nt | nt | nt | 84.7 ± 3.8 | 73.3 ± 4.3 |
nt: Not tested. DCM: dichloromethane.