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. 2017 Jan 6;22(1):93. doi: 10.3390/molecules22010093

Table 2.

Biological activities of different compounds present in cotton.

Compounds Biological Activity References
Terpenes
camphene Aromatic properties, antioxidants effects [21]
limonene Flavouring properties. gastro-protective effects, anti-cancer and anti-inflammatory activity [28,142]
myrcene Analgesic effects, anti-microbial activity, anti-inflammatory activity, anti-catabolic activity [171,172]
α and β-pinene Gastro-protective effects, anti- microbial and ant-inflammatory effects [28,174,180]
sabinene Anti-microbial activity, anti-oxidant activity [21]
α-thujene Pungent activity [21]
caryophyllene Ant-inflammatory effects, anti-microbial activity, regulation of cellular lipid metabolism, flavouring properties [27,32,181,182]
farnesene Anti-oxidant effects [179]
humulene Anti-inflammatory properties, aromatic properties and cytotoxic activity [29,32]
bisabolol Aromatic properties, anti-inflammatory effects, anti-carcinogenic activity, anti-microbial and anti-oxidative properties [28,183,184]
caryophyllene oxide Cytotoxic activity, phytogrowth inhibition, analgesic and anti-inflammatory activity [177] [26,185]
3,10-dihydroxy-1,3,5,7-cadinatetraen-9-one Phytoalexin, antifungal agent [92,186]
β-sitosterol Antimicrobial activity, anti-hypercholesteraemic and anti-inflammatory activity [18,28]
strigol Germination stimulant [96,187,188]
2,3,9-trihydroxy-1,3,5,7,9-cadinapentaen-14-al; 3-Me ether Phytoalexin [99]
2,8,9-trihydroxy-1,3,5,7,9-cadinapentaen-14-al; 8-deoxy Antifungal activity [92]
Phenols
chlorogenic acid Anti-oxidant and anti-mutagenic activity [144]
gallic acid Antioxidant activity, cytotoxic activity [189,190]
4-hydroxybenzoic acid Anti-microbial activity, used as preservative, oestrogenic activity, anti-inflammatory and anti-oxidant activity [175,176,191]
gossypol; (+)-form Contraceptive and hypokalemic activity [30,192,193]
3,3′,4′,5,7-pentahydroxyflavan; (2S,3R)-form Cytotoxic and phytotoxic activity [194,195]
3,3′,4′,5,7-pentahydroxyflavone; 3′-O-β-d-glucopyranoside Enzyme inhibitor, cytotoxic, anti-oxidant activity [196]
scopoletin Anti-spasmodic and anti-inflammatory activity [19]
Fatty acids
11,14-eicosadienoic acid Hormonal activity [18]
hexadecanoic acid Anti-microbial and anti-inflammatory activity [197]
octadecanoic acid Pharmaceutical excipient, surfactant and softening activity [198]
9-octadecenoic acid; (Z)-form Insecticidal, anti-bacterial and fungicidal activity [199,200,201]
tetradecanoic acid Defoaming agent, flavour adjuvant used in food processing [202]
Carbohydrates
cellulose Capsule and tablet diluent [203]
Proteins
3-phosphoglycerate phosphatase Enzyme activity [119]
vicilin Anti-hypertensive activity [204]