Figure 1.

Cytotoxic activity of in vitro of Compounds 1–6 against HeLa and A2780 tumor cells. * Data are reported as IC₅₀ values determined by MTT assay after 24 h of continuous exposure to each compound. The values were calculated using sigmoidal dose-response relationship. The data represents mean values ± SEM (standard error of mean) of at least three independent experiments.

Compounds	IC50 (μM)
	HeLa	A2780
Cisplatin	20.10 ± 0.22	12.30 ± 0.22
1	22.42 ± 0.24	11.65 ± 0.21
2	28.55 ± 0.25	26.49 ± 0.21
3	19.42 ± 0.22	12.99 ± 0.50
4	33.98 ± 0.31	28.08 ± 0.23
5	19.84 ± 0.33	19.66 ± 0.50
6	34.72 ± 0.25	20.15 ± 0.26