Table 2.
Effect of the essential oils from the selected Mentha species on carrageenan-induced rat paw edema.
| Group | Dose | Edema 1 h (mL) | Edema 2 h (mL) | Edema 3 h (mL) | Edema 4 h (mL) |
|---|---|---|---|---|---|
| (% inhib.) | (% inhib.) | (% inhib.) | (% inhib.) | ||
| Control (vehicle) | - | 0.56 ± 0.11 | 1.30 ± 0.13 | 2.00 ± 0.20 | 2.34 ± 0.27 |
| EOMPA | 500 mg/kg | 0.36 ± 0.20 | 0.96 ± 0.40 | 1.40 ± 0.64 | 1.12 ± 0.84 * |
| (35.71%) | (25.15%) | (30.00%) | (52.13) | ||
| EOMPA | 250 mg/kg | 0.42 ± 0.04 | 1.11 ± 0.53 | 1.69 ± 0.73 | 1.80 ± 0.46 |
| (25.00%) | (14.61%) | (15.50%) | (23.07%) | ||
| EOMPA | 125 mg/kg | 0.50 ± 0.15 | 1.21 ± 0.66 | 1.81 ± 0.98 | 2.03 ± 1.18 |
| (10.71%) | (6.92%) | (9.50%) | (13.24%) | ||
| EOMSP | 500 mg/kg | 0.36 ± 0.17 | 0.52 ± 0.28 * | 0.74 ± 0.26 * | 0.88 ± 0.26 * |
| (35.71%) | (60.00%) | (63.00%) | (62.39%) | ||
| EOMSP | 250 mg/kg | 0.44 ± 0.27 | 0.78 ± 0.19 * | 1.23 ± 0.46 | 1.54 ± 0.86 |
| (21.42%) | (40.00%) | (38.50%) | (34.18%) | ||
| EOMSP | 125 mg/kg | 0.50 ± 0.37 | 1.03 ± 0.69 | 1.68 ± 1.13 | 2.01 ± 0.64 |
| (10.71%) | (20.76%) | (16.00%) | (14.10%) | ||
| EOMSU | 500 mg/kg | 0.54 ± 0.35 | 0.98 ± 0.64 | 1.23 ± 0.89 | 1.41 ± 0.78 |
| (3.57%) | (24.61%) | (38.50%) | (39.74%) | ||
| EOMSU | 250 mg/kg | 0.63 ± 0.22 | 1.20 ± 0.80 | 1.56 ± 0.73 | 1.84 ± 0.98 |
| (-) | (7.69%) | (22.00%) | (21.36%) | ||
| EOMSU | 125 mg/kg | 0.70 ± 0.31 | 1.42 ± 0.69 | 1.79 ± 0.46 | 2.13 ± 1.36 |
| (-) | (-) | (10.5%) | (8.9%) | ||
| Diclofenac | 20 mg/kg | 0.36 ± 0.06 * | 0.55 ± 0.11 * | 0.68 ± 0.08 * | 1.06 ± 0.17 * |
| (35.71%) | (57.69%) | (66.00%) | (54.70%) |
* Statistically significant, p ≤ 0.05. Values are expressed as Mean ± SD.