Table 4.
Effect of the essential oils from the selected Mentha species in the hot plate test in mice.
| Group | Response (s) at 0 min (PAS) | Response (s) at 30 min (PAS) | Response (s) at 60 min (PAS) | Response (s) at 90 min (PAS) | Response (s) at 120 min (PAS) |
|---|---|---|---|---|---|
| Control (Vehicle) | 8.78 ± 2.18 | 9.12 ± 1.94 | 8.19 ± 1.53 | 7.85 ± 1.80 | 7.13 ± 1.96 |
| (-) | (-) | (-) | (-) | (-) | |
| EOMPA 500 mg/kg | 9.05 ± 1.76 | 15.89 ± 2.27 | 20.98 ± 6.17 * | 23.44 ± 4.72 * | 25.12 ± 8.47 * |
| (-) | (43.04%) | (56.86%) | (61.39%) | (63.97%) | |
| EOMPA 250 mg/kg | 10.34 ± 2.20 | 13.44 ± 3.67 | 17.39 ± 4.99 * | 19.89 ± 4.63 | 21.27 ± 5.46 * |
| (-) | (23.06%) | (40.54%) | (48.01%) | (51.38%) | |
| EOMPA 125 mg/kg | 9.42 ± 1.96 | 11.29 ± 2.16 | 14.52 ± 4.21 | 17.11 ± 3.92 | 18.41 ± 4.52 |
| (-) | (16.56%) | (35.12%) | (44.94%) | (48.83%) | |
| EOMSP 500 mg/kg | 9.84 ± 1.98 | 18.23 ± 3.76 | 24.75 ± 6.71 * | 27.42 ± 6.06 * | 28.44 ± 4.77 * |
| (-) | (46.02%) | (60.24%) | (64.11%) | (65.40%) | |
| EOMSP 250 mg/kg | 10.31 ± 0.84 | 14.97 ± 3.70 | 19.42 ± 4.63 | 22.93 ± 6.35 * | 24.03 ± 6.15 * |
| (-) | (31.12%) | (46.91%) | (55.03%) | (57.09%) | |
| EOMSP 125 mg/kg | 9.24 ± 1.87 | 12.19 ± 3.90 | 15.55 ± 3.09 * | 18.32 ± 4.57 * | 20.84 ± 5.82 * |
| (-) | (24.20%) | (40.57%) | (49.56%) | (55.66%) | |
| EOMSU 500 mg/kg | 10.11 ± 3.09 | 13.42 ± 3.23 | 18.11 ± 2.04 | 20.75 ± 4.54 * | 21.04 ± 6.64 * |
| (-) | (24.66%) | (44.17%) | (51.27%) | (51.94%) | |
| EOMSU 250 mg/kg | 9.19 ± 1.96 | 11.41 ± 2.74 | 15.14 ± 4.41 | 17.02 ± 5.15 | 16.14 ± 3.90 |
| (-) | (19.45%) | (39.29%) | (46.00%) | (43.06%) | |
| EOMSU 125 mg/kg | 10.04 ± 2.11 | 10.11 ± 1.76 | 13.45 ± 2.98 | 14.25 ± 4.50 | 13.89 ± 3.70 |
| (-) | (6.9%) | (25.35%) | (29.54%) | (27.71%) | |
| Morphine 10 mg/kg | 10.23 ± 2.92 | 11.50 ± 4.21 | 35.63 ± 7.58 * | 38.72 ± 6.64 * | 37.45 ± 6.77 * |
| (-) | (11.04%) | (71.28%) | (73.57%) | (72.68) |
* Statistically significant, p ≤ 0.05. Values are expressed as Mean ± SD.